HCLS1 antibody (pTyr378)

Catalog No. ABIN7221460

The Rabbit Polyclonal anti-HCLS1 antibody has been validated for WB and ELISA. It is suitable to detect HCLS1 in samples from Human.

Quick Overview for HCLS1 antibody (pTyr378) (ABIN7221460)

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCLS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCLS1 Antibody

Binding Specificity: pTyr378

Purpose: Lck BP-1 (phospho Tyr378) Polyclonal Antibody

Specificity: Phospho-Lck BP-1 (Y378) Polyclonal Antibody detects endogenous levels of Lck BP-1 protein only when phosphorylated at Y378.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Lck BP-1 Phospho-Tyr378

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HCLS1

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Alternative Name: Lck BP-1

Background: Rabbit Anti-Lck BP-1 (phospho Tyr378) Polyclonal Antibody,HCLS1, HS1, Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75,Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.,Hematopoietic lineage cell-specific protein

Molecular Weight: observerd band 78kDa

Gene ID: 3059

UniProt: P14317

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location