HOXD8 antibody (AA 210-290)
Quick Overview for HOXD8 antibody (AA 210-290) (ABIN7221548)
Target
See all HOXD8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 210-290
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Purpose
- HoxD8 Polyclonal Antibody
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Specificity
- HoxD8 Polyclonal Antibody detects endogenous levels of HoxD8 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human HoxD8 at AA range: 210-290
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HOXD8 (Homeobox D8 (HOXD8))
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Alternative Name
- HoxD8
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Background
- Rabbit Anti-HoxD8 Polyclonal Antibody,HOXD8, HOX4E, Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4,HOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.,Homeobox protein Hox-D8
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Molecular Weight
- observerd band 32kDa
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Gene ID
- 3234
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UniProt
- P13378
Target
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