HCN1 antibody (AA 380-460)

Catalog No. ABIN7228868

The Rabbit Polyclonal anti-HCN1 antibody has been validated for WB and ELISA. It is suitable to detect HCN1 in samples from Human, Rat and Mouse.

Quick Overview for HCN1 antibody (AA 380-460) (ABIN7228868)

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCN1 Antibody

Binding Specificity: AA 380-460

Purpose: HCN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HCN1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human HCN1 protein at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HCN1

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Alternative Name: HCN1

Background: Rabbit Anti-HCN1 Polyclonal Antibody,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, Brain cyclic nucleotide-gated channel 1, BCNG-1,HCN1 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1) is a Protein Coding gene. Among its related pathways are Potassium Channels and Transmission across Chemical Synapses. The membrane protein encoded by HCN1 is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes.,HCN1

Molecular Weight: observerd band 97kDa

Gene ID: 348980

UniProt: O60741

Pathways: Asymmetric Protein Localization