HCN4 antibody (AA 600-680)

Catalog No. ABIN7228872

The Rabbit Polyclonal anti-HCN4 antibody has been validated for WB and ELISA. It is suitable to detect HCN4 in samples from Human, Rat and Mouse.

Quick Overview for HCN4 antibody (AA 600-680) (ABIN7228872)

Target: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCN4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCN4 Antibody

Binding Specificity: AA 600-680

Purpose: HCN4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HCN4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human HCN4 protein at AA range: 600-680

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HCN4

Target: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Alternative Name: HCN4

Background: Rabbit Anti-HCN4 Polyclonal Antibody,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in HCN4 have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.,HCN4

Molecular Weight: observerd band 132kDa

Gene ID: 10021

UniProt: Q9Y3Q4