IRGM antibody (AA 101-150)

Catalog No. ABIN7229186

The Rabbit Polyclonal anti-IRGM antibody has been validated for WB and ELISA. It is suitable to detect IRGM in samples from Human.

Quick Overview for IRGM antibody (AA 101-150) (ABIN7229186)

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRGM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRGM Antibody

Binding Specificity: AA 101-150

Purpose: IRGM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IRGM protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human IRGM protein at AA range: 101-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IRGM

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Alternative Name: IRGM

Background: Rabbit Anti-IRGM Polyclonal Antibody,Immunity-related GTPase family M protein, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47,IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of IRGM are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.,IRGM

Molecular Weight: observerd band 19kDa

Gene ID: 345611

UniProt: A1A4Y4