Importin 5 antibody

Catalog No. ABIN7229178

This Rabbit Polyclonal antibody specifically detects Importin 5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Importin 5 antibody (ABIN7229178)

Target: Importin 5 (IPO5)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Importin 5 Antibody

Purpose: IPO5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IPO5 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human IPO5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Importin 5

Target: Importin 5 (IPO5)

Alternative Name: IPO5

Background: Rabbit Anti-IPO5 Polyclonal Antibody,Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5,IPO5 (Importin 5) is a Protein Coding gene. Diseases associated with IPO5 include Hiv-1. Among its related pathways are Development_TGF-beta receptor signaling and HIV Life Cycle. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.,IPO5

Molecular Weight: observerd band 120kDa

Gene ID: 3843

UniProt: O00410

Pathways: Protein targeting to Nucleus