Integrin alpha 1 antibody (AA 920-980)

Catalog No. ABIN7229164

The Rabbit Polyclonal anti-Integrin alpha 1 antibody has been validated for ELISA and IHC (p). It is suitable to detect Integrin alpha 1 in samples from Human.

Quick Overview for Integrin alpha 1 antibody (AA 920-980) (ABIN7229164)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Integrin alpha 1 Antibody

Binding Specificity: AA 920-980

Purpose: Integrin α1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Integrin α1

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Integrin alpha1 protein at AA range: 920-980

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: Integrin alpha1

Background: Rabbit Anti-Integrin α1 Polyclonal Antibody,Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD antigen CD49a,Integrin α1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.,Integrin α1

Gene ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex