ITGAD antibody (Internal Region)

Catalog No. ABIN7218440

This Rabbit Polyclonal antibody specifically detects ITGAD in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ITGAD antibody (Internal Region) (ABIN7218440)

Target: ITGAD (Integrin alpha D (ITGAD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGAD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGAD Antibody

Binding Specificity: Internal Region

Purpose: Integrin αD Polyclonal Antibody

Specificity: Integrin αD Polyclonal Antibody detects endogenous levels of Integrin αD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Integrin alphaD

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ITGAD

Target: ITGAD (Integrin alpha D (ITGAD))

Alternative Name: Integrin alphaD

Background: Rabbit Anti-Integrin αD Polyclonal Antibody,ITGAD, Integrin alpha-D, ADB2, CD11 antigen-like family member D, Leukointegrin alpha D, CD11d,ITGAD belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.,Integrin alpha-D

Molecular Weight: observerd band 127kDa

Gene ID: 3681

UniProt: Q13349

Pathways: Activated T Cell Proliferation, Integrin Complex