ITGB1BP2 antibody (AA 10-90)

Catalog No. ABIN7229198

The Rabbit Polyclonal anti-ITGB1BP2 antibody is suitable to detect ITGB1BP2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for ITGB1BP2 antibody (AA 10-90) (ABIN7229198)

Target: ITGB1BP2 (Integrin beta 1 Binding Protein (Melusin) 2 (ITGB1BP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1BP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITGB1BP2 Antibody

Binding Specificity: AA 10-90

Purpose: ITBP2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ITBP2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ITBP2 protein at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ITGB1BP2

Target: ITGB1BP2 (Integrin beta 1 Binding Protein (Melusin) 2 (ITGB1BP2))

Alternative Name: ITBP2

Background: Rabbit Anti-ITBP2 Polyclonal Antibody,Integrin beta-1-binding protein 2, Melusin,ITGB1BP2 encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of ITGB1BP2 indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains.,ITBP2

Molecular Weight: observerd band 38kDa

Gene ID: 26548

UniProt: Q9UKP3