ITIH2 antibody (Cleaved-Asp702)

Catalog No. ABIN7212528

The Rabbit Polyclonal anti-ITIH2 antibody has been validated for WB and ELISA. It is suitable to detect ITIH2 in samples from Human.

Quick Overview for ITIH2 antibody (Cleaved-Asp702) (ABIN7212528)

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITIH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITIH2 Antibody

Binding Specificity: AA 630-710, Cleaved-Asp702

Purpose: Cleaved-ITI-H2 (D702) Polyclonal Antibody

Specificity: Cleaved-ITI-H2 (D702) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H2 protein resulting from cleavage adjacent to D702.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ITI-H2 at AA range: 630-710

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ITIH2

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Alternative Name: ITI-H2

Background: Rabbit Anti-Cleaved-ITI-H2 (D702) Polyclonal Antibody,ITIH2, IGHEP2, Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2, Inter-alpha-trypsin inhibitor complex component II, Serum-derived hyaluronan-associated protein, SHAP,The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322], Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009],Inter-alpha-trypsin inhibitor heavy chain H2

Molecular Weight: observerd band 72kDa

Gene ID: 3698

UniProt: P19823

Pathways: Glycosaminoglycan Metabolic Process