ICAM-3/CD50 antibody

Catalog No. ABIN7221636

This Rabbit Polyclonal antibody specifically detects ICAM-3/CD50 in WB, IF and ELISA. It exhibits reactivity toward Human.

Quick Overview for ICAM-3/CD50 antibody (ABIN7221636)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-ICAM-3/CD50 Antibody

Purpose: CD50 Polyclonal Antibody

Specificity: CD50 Polyclonal Antibody detects endogenous levels of CD50 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human CD50 around the non-phosphorylation site of S518

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: CD50

Background: Rabbit Anti-CD50 Polyclonal Antibody,ICAM3, Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD antigen CD50,The intercellular adhesion molecule 3 encoded by ICAM3 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.,Intercellular adhesion molecule 3

Molecular Weight: observerd band 42-60kDa

Gene ID: 3385

UniProt: P32942