IL17RA antibody (AA 110-190)

Catalog No. ABIN7220792

This Rabbit Polyclonal antibody specifically detects IL17RA in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL17RA antibody (AA 110-190) (ABIN7220792)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RA Antibody

Binding Specificity: AA 110-190

Purpose: IL-17Rα Polyclonal Antibody

Specificity: IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human IL-17Ralpha at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL-17Ralpha

Background: Rabbit Anti-IL-17Rα Polyclonal Antibody,IL17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD antigen CD217,Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.,Interleukin-17 receptor A

Molecular Weight: observerd band 90kDa

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome