IL-19 antibody (AA 51-100)

Catalog No. ABIN7229104

This Rabbit Polyclonal antibody specifically detects IL-19 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for IL-19 antibody (AA 51-100) (ABIN7229104)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL-19 Antibody

Binding Specificity: AA 51-100

Purpose: IL-19 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IL-19

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human IL-19 protein at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Alternative Name: IL-19

Background: Rabbit Anti-IL-19 Polyclonal Antibody,Interleukin-19, IL-19, Melanoma differentiation-associated protein-like protein, NG.1,The protein encoded by IL19 is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. IL19 (Interleukin 19) is a Protein Coding gene. Diseases associated with IL19 include Spongiotic Dermatitis and Psoriasis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.,IL-19

Molecular Weight: observerd band 20kDa

Gene ID: 29949

UniProt: Q9UHD0