IL-22 antibody (C-Term)

Catalog No. ABIN7226698

The Rabbit Polyclonal anti-IL-22 antibody has been validated for WB and ELISA. It is suitable to detect IL-22 in samples from Human, Mouse and Rat.

Quick Overview for IL-22 antibody (C-Term) (ABIN7226698)

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-22 Antibody

Binding Specificity: C-Term

Purpose: IL-22 Polyclonal Antibody

Specificity: IL-22 Polyclonal Antibody detects endogenous levels of IL-22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human IL-22

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL-22

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Alternative Name: IL-22

Background: Rabbit Anti-IL-22 Polyclonal Antibody,IL22, ILTIF, ZCYTO18, Interleukin-22, IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF,IL-10-related T cell-derived inducible factor (IL-22, also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22 % amino acid identity with IL-10. Additionally, IL-22 is induced by IL-9 in thymic lymphomas and by lectins in freshly isolated splenocytes. IL-22 is found in both the thymus and brain, which suggests that the role of this factor is not restricted to the immune system. IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family. In contrast to IL-10, IL-22 does not inhibit the production of proinflammatory cytokines by monocytes in response to lipopolysaccharide nor does it impact IL-10 function on monocytes, but it has modest inhibitory effects on IL-4 production from Th2 T cells.,Interleukin-22

Molecular Weight: observerd band 22kDa

Gene ID: 50616

UniProt: Q9GZX6