IL-8 antibody (C-Term)

Catalog No. ABIN7212178

This anti-IL-8 antibody is a Mouse Monoclonal antibody detecting IL-8 in IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for IL-8 antibody (C-Term) (ABIN7212178)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-8 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 13F8

Product Details anti-IL-8 Antibody

Binding Specificity: C-Term

Purpose: IL-8 Mouse Monoclonal Antibody (13F8)

Specificity: IL-8 protein detects endogenous levels of IL8.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogen: Synthetic C-TERM Peptide of IL-8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8

Background: Mouse Anti-IL-8 Mouse Monoclonal Antibody (13F8),IL8,The protein encoded by CXCL8 (C-X-C motif chemokine ligand 8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. CXCL8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. CXCL8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.,IL8

Molecular Weight: observerd band 11kDa

Gene ID: 3576

UniProt: P10145

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy