Inversin antibody

Catalog No. ABIN7229172

This Rabbit Polyclonal antibody specifically detects Inversin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Inversin antibody (ABIN7229172)

Target: Inversin (INVS)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Inversin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Inversin Antibody

Purpose: INVS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of INVS protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human INVS protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Inversin

Target: Inversin (INVS)

Alternative Name: INVS

Background: Rabbit Anti-INVS Polyclonal Antibody,Inversin, Inversion of embryo turning homolog, Nephrocystin-2,INVS (Inversin) is a Protein Coding gene. Diseases associated with INVS include Nephronophthisis 2, Infantile and Nephronophthisis 16. Among its related pathways are Wnt Signaling Pathway and Pluripotency. INVS encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in INVS have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for INVS.,INVS

Molecular Weight: observerd band 117kDa

Gene ID: 27130

UniProt: Q9Y283