JTB antibody (AA 20-100)

Catalog No. ABIN7219176

The Rabbit Polyclonal anti-JTB antibody has been validated for WB and ELISA. It is suitable to detect JTB in samples from Human.

Quick Overview for JTB antibody (AA 20-100) (ABIN7219176)

Target: JTB (Jumping Translocation Breakpoint (JTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JTB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-JTB Antibody

Binding Specificity: AA 20-100

Purpose: JTB Polyclonal Antibody

Specificity: JTB Polyclonal Antibody detects endogenous levels of JTB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human JTB at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for JTB

Target: JTB (Jumping Translocation Breakpoint (JTB))

Alternative Name: JTB

Background: Rabbit Anti-JTB Polyclonal Antibody,JTB, HSPC222, Protein JTB, Jumping translocation breakpoint protein, Prostate androgen-regulated protein, PAR protein,Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.,Protein JTB

Molecular Weight: observerd band 17kDa

Gene ID: 10899

UniProt: O76095