Kallikrein 8 antibody (Cleaved-Val33)

Catalog No. ABIN7212480

The Rabbit Polyclonal anti-Kallikrein 8 antibody (ABIN7212480) specifically detects Kallikrein 8 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Kallikrein 8 antibody (Cleaved-Val33) (ABIN7212480)

Target: Kallikrein 8 (KLK8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Kallikrein 8 Antibody

Binding Specificity: AA 30-110, Cleaved-Val33

Purpose: Cleaved-KLK8 (V33) Polyclonal Antibody

Specificity: Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human KLK8 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Kallikrein 8

Target: Kallikrein 8 (KLK8)

Alternative Name: KLK8

Background: Rabbit Anti-Cleaved-KLK8 (V33) Polyclonal Antibody,KLK8, NRPN, PRSS19, TADG14, Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein,Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK8 is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. Kallikrein related peptidase 8 may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of KLK8 results in multiple transcript variants encoding different isoforms.,Kallikrein-8

Molecular Weight: observerd band 24kDa

Gene ID: 11202

UniProt: O60259

Pathways: Complement System