KRT16 antibody (AA 390-470)
Quick Overview for KRT16 antibody (AA 390-470) (ABIN7214482)
Target
See all KRT16 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 390-470
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Purpose
- Cytokeratin 16 Polyclonal Antibody
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Specificity
- Cytokeratin 16 Polyclonal Antibody detects endogenous levels of Cytokeratin 16 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human Cytokeratin 16 at AA range: 390-470
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- KRT16 (Keratin 16 (KRT16))
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Alternative Name
- Cytokeratin 16
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Background
- Rabbit Anti-Cytokeratin 16 Polyclonal Antibody,KRT16, KRT16A, Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16,Keratin 16 encoded by KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.,Keratin type I cytoskeletal 16
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Molecular Weight
- observerd band 52kDa
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Gene ID
- 3868
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UniProt
- P08779
Target
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