LGALS12 antibody (pSer736)

Catalog No. ABIN7219010

The Rabbit Polyclonal anti-LGALS12 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect LGALS12 in samples from Human.

Quick Overview for LGALS12 antibody (pSer736) (ABIN7219010)

Target: LGALS12 (Lectin, Galactoside-Binding, Soluble, 12 (LGALS12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGALS12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LGALS12 Antibody

Binding Specificity: pSer736

Purpose: GRIP-1 (phospho Ser736) Polyclonal Antibody

Specificity: Phospho-GRIP-1 (S736) Polyclonal Antibody detects endogenous levels of GRIP-1 protein only when phosphorylated at S736.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human GRIP-1 Phospho-Ser736

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for LGALS12

Target: LGALS12 (Lectin, Galactoside-Binding, Soluble, 12 (LGALS12))

Alternative Name: GRIP-1

Background: Rabbit Anti-GRIP-1 (phospho Ser736) Polyclonal Antibody,glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1, GRIP, GRIP-1,Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).,Nuclear receptor coactivator 2

Molecular Weight: observerd band 180kDa

Gene ID: 10499

UniProt: Q15596