LRP1B antibody (AA 200-280)

Catalog No. ABIN7229444

This Rabbit Polyclonal antibody specifically detects LRP1B in IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for LRP1B antibody (AA 200-280) (ABIN7229444)

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP1B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LRP1B Antibody

Binding Specificity: AA 200-280

Purpose: LRP1B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LRP1B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human LRP1B protein at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for LRP1B

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Alternative Name: LRP1B

Background: Rabbit Anti-LRP1B Polyclonal Antibody,Low-density lipoprotein receptor-related protein 1B, LRP-1B, Low-density lipoprotein receptor-related protein-deleted in tumor, LRP-DIT,LRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor family have roles related to clearance of extracellular ligand and are proposed to be involved in extracellular signal transduction. silencing and down-expression of LRP1B as been observed in renal cell carcinoma and thyroid cancer. Further Deletion of LRP1B has been associated with chemotherapy resistance in high-grade serous cancers.,LRP1B

Molecular Weight: observerd band 505kDa

Gene ID: 53353

UniProt: Q9NZR2