LTA antibody (Internal Region)

Catalog No. ABIN7217348

The Rabbit Polyclonal anti-LTA antibody (ABIN7217348) specifically detects LTA in WB and ELISA. The antibody is reactive with Human, Rat, Mouse and Monkey samples.

Quick Overview for LTA antibody (Internal Region) (ABIN7217348)

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LTA Antibody

Binding Specificity: Internal Region

Purpose: TNF-β Polyclonal Antibody

Specificity: TNF-β Polyclonal Antibody detects endogenous levels of TNF-β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human TNF-beta

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: TNF-beta

Target Type: Chemical

Background: Rabbit Anti-TNF-β Polyclonal Antibody,LTA, TNFB, TNFSF1, Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1,The lymphotoxin-alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. Lymphotoxin-alpha is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.,Lymphotoxin-alpha

Molecular Weight: observerd band 22kDa

Gene ID: 4049

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process