M-AChR M5 (AA 260-340) antibody
Quick Overview for M-AChR M5 (AA 260-340) antibody (ABIN7219312)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 260-340
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Purpose
- mAChR M5 Polyclonal Antibody
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Specificity
- MAChR M5 Polyclonal Antibody detects endogenous levels of mAChR M5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human mAChR M5 at AA range: 260-340
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- M-AChR M5
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Alternative Name
- mAChR M5
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Background
- Rabbit Anti-mAChR M5 Polyclonal Antibody,CHRM5, Muscarinic acetylcholine receptor M5,The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, stimulation of this receptor is known to increase cyclic AMP levels.,Muscarinic acetylcholine receptor M5
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Molecular Weight
- observerd band 60kDa
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Gene ID
- 1133
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UniProt
- P08912
Target
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