WASF2 antibody (AA 131-230) (Cy5.5)

Catalog No. ABIN716281

This Rabbit Polyclonal antibody specifically detects WASF2 in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for WASF2 antibody (AA 131-230) (Cy5.5) (ABIN716281)

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF2 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-WASF2 Antibody (Cy5.5)

Binding Specificity: AA 131-230

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WASF2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for WASF2

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Alternative Name: WASF2

Background:

Synonyms: Protein WAVE-2, SCAR 2, SCAR, SCAR2, Verprolin homology domain-containing protein 2, WASF2, WASF2_HUMAN, WASP family protein member 2, WASP-family protein member 2, WAVE 2, WAVE2, Wiskott-Aldrich syndrome protein family member 2, Wiskott-Aldrich syndrome protein family verprolin-homologous protein, DICTYOSTELIUM, WASF2_HUMAN.

Background: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID: 10163

Pathways: RTK Signaling