MMP15 antibody (Cleaved-Tyr132)

Catalog No. ABIN7212490

This Rabbit Polyclonal antibody specifically detects MMP15 in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for MMP15 antibody (Cleaved-Tyr132) (ABIN7212490)

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MMP15 Antibody

Binding Specificity: AA 90-170, Cleaved-Tyr132

Purpose: Cleaved-MMP-15 (Y132) Polyclonal Antibody

Specificity: Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MMP-15 at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Alternative Name: MMP-15

Background: Rabbit Anti-Cleaved-MMP-15 (Y132) Polyclonal Antibody,MMP15, Matrix metalloproteinase-15, MMP-15, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2,MMP15 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 15 may play a role in cancer progression.,Matrix metalloproteinase-15

Molecular Weight: observerd band 61kDa

Gene ID: 4324

UniProt: P51511