MXD4 antibody (AA 10-90)

Catalog No. ABIN7219076

This Rabbit Polyclonal antibody specifically detects MXD4 in ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for MXD4 antibody (AA 10-90) (ABIN7219076)

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MXD4 Antibody

Binding Specificity: AA 10-90

Purpose: Mad 4 Polyclonal Antibody

Specificity: Mad 4 Polyclonal Antibody detects endogenous levels of Mad 4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Mad 4 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MXD4

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Alternative Name: Mad 4

Background: Rabbit Anti-Mad 4 Polyclonal Antibody,MXD4, BHLHC12, MAD4, Max dimerization protein 4, Max dimerizer 4, Class C basic helix-loop-helix protein 12, bHLHc12, Max-associated protein 4, Max-interacting transcriptional repressor MAD4,MXD4 is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.,Max dimerization protein 4

Gene ID: 10608

UniProt: Q14582