MIA3 antibody (AA 1110-1190)

Catalog No. ABIN7229662

This Rabbit Polyclonal antibody specifically detects MIA3 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for MIA3 antibody (AA 1110-1190) (ABIN7229662)

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIA3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MIA3 Antibody

Binding Specificity: AA 1110-1190

Purpose: MIA3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MIA3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MIA3 protein at AA range: 1110-1190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MIA3

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Alternative Name: MIA3

Background: Rabbit Anti-MIA3 Polyclonal Antibody,Transport and Golgi organization protein 1 homolog, TANGO1, C219-reactive peptide, D320, Melanoma inhibitory activity protein 3,MIA3 (MIA Family Member 3, ER Export Factor) is a Protein Coding gene. Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum.,MIA3

Molecular Weight: observerd band 209kDa

Gene ID: 375056

UniProt: Q5JRA6