MRPL40 antibody (AA 60-140)

Catalog No. ABIN7221358

This anti-MRPL40 antibody is a Rabbit Polyclonal antibody detecting MRPL40 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for MRPL40 antibody (AA 60-140) (ABIN7221358)

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL40 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MRPL40 Antibody

Binding Specificity: AA 60-140

Purpose: MRP-L22 Polyclonal Antibody

Specificity: MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MRP-L22 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MRPL40

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Alternative Name: MRP-L22

Background: Rabbit Anti-MRP-L22 Polyclonal Antibody,MRPL22, MRPL25, RPML25, HSPC158, 39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22, 39S ribosomal protein L25, mitochondrial, L25mt, MRP-L25,Mammalian mitochondrial ribosomal proteins are encoded by MRPL22 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to MRPL22 is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for MRPL22.,39S ribosomal protein L22 mitochondrial

Molecular Weight: observerd band 24kDa

Gene ID: 29093

UniProt: Q9NWU5