MRPL40 antibody

Catalog No. ABIN7247570

Product Details anti-MRPL40 Antibody

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL40 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human MRPL40

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.44 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL40

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Alternative Name: MRPL40 (MRPL40 Products)

Synonyms: Nlvcf antibody, CG5242 antibody, Dmel\\CG5242 antibody, MRPL22(24) antibody, mRpL22-24 antibody, MRP-L22 antibody, MRPL22 antibody, NLVCF antibody, URIM antibody, fj54c06 antibody, wu:fj54c06 antibody, zgc:103495 antibody, SPAC644.02 antibody, mitochondrial ribosomal protein L40 antibody, mitochondrial ribosomal protein L40 S homeolog antibody, mitochondrial ribosomal protein L40-like antibody, 39S ribosomal protein L40, mitochondrial antibody, mitochondrial 54S ribosomal protein YmL40 antibody, mitochondrial ribosomal protein subunit L40 (predicted) antibody, Mrpl40 antibody, mRpL40 antibody, MRPL40 antibody, mrpl40 antibody, mrpl40.S antibody, LOC727014 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 24 kDa

UniProt: Q9NQ50