MRPL48 antibody (AA 130-210)

Catalog No. ABIN7223078

The Rabbit Polyclonal anti-MRPL48 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect MRPL48 in samples from Human and Mouse.

Quick Overview for MRPL48 antibody (AA 130-210) (ABIN7223078)

Target: MRPL48 (Mitochondrial Ribosomal Protein L48 (MRPL48))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL48 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MRPL48 Antibody

Binding Specificity: AA 130-210

Purpose: MRP-L48 Polyclonal Antibody

Specificity: MRP-L48 Polyclonal Antibody detects endogenous levels of MRP-L48 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human MRP-L48 at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MRPL48

Target: MRPL48 (Mitochondrial Ribosomal Protein L48 (MRPL48))

Alternative Name: MRP-L48

Background: Rabbit Anti-MRP-L48 Polyclonal Antibody,MRPL48, CGI-118, HSPC290, 39S ribosomal protein L48, mitochondrial, L48mt, MRP-L48,Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL48 (mitochondrial ribosomal protein L48) encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.,39S ribosomal protein L48 mitochondrial

Molecular Weight: observerd band 23kDa

Gene ID: 51642

UniProt: Q96GC5