MTIF2 antibody (AA 450-530)
Quick Overview for MTIF2 antibody (AA 450-530) (ABIN7229022)
Target
See all MTIF2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 450-530
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Purpose
- IF2M Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of IF2M protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human IF2M protein at AA range: 450-530
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))
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Alternative Name
- IF2M
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Background
- Rabbit Anti-IF2M Polyclonal Antibody,Translation initiation factor IF-2, mitochondrial, IF-2Mt,MTIF2 (Mitochondrial Translational Initiation Factor 2) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.,IF2M
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Molecular Weight
- observerd band 79kDa
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Gene ID
- 4528
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UniProt
- P46199
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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