Moesin/ezrin/radixin (pThr558) antibody

Catalog No. ABIN7222552

This Rabbit Polyclonal antibody specifically detects Moesin/ezrin/radixin in ELISA, WB, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Moesin/ezrin/radixin (pThr558) antibody (ABIN7222552)

Target: Moesin/ezrin/radixin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: pThr558

Purpose: Moesin/Ezrin/Radixin (phospho Thr558) Polyclonal Antibody

Specificity: Phospho-Moesin/Ezrin/Radixin (T558) Polyclonal Antibody detects endogenous levels of Moesin/Ezrin/Radixin protein only when phosphorylated at T558.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Moesin/Ezrin/Radixin Phospho-Thr558

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: Moesin/ezrin/radixin

Background: Rabbit Anti-Moesin/Ezrin/Radixin (phospho Thr558) Polyclonal Antibody,MSN, Moesin, Membrane-organizing extension spike protein, RDX, Radixin, EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81,Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.,Moesin

Molecular Weight: observerd band 67kDa

Gene ID: 4478, 5962