Myomesin 1 antibody (AA 800-880)

Catalog No. ABIN7225642

This anti-Myomesin 1 antibody is a Rabbit Polyclonal antibody detecting Myomesin 1 in ELISA and IHC (p). Suitable for Human.

Quick Overview for Myomesin 1 antibody (AA 800-880) (ABIN7225642)

Target: Myomesin 1 (MYOM1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myomesin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Myomesin 1 Antibody

Binding Specificity: AA 800-880

Purpose: Myomesin-1 Polyclonal Antibody

Specificity: Myomesin-1 Polyclonal Antibody detects endogenous levels of Myomesin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Myomesin-1 at AA range: 800-880

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Myomesin 1

Target: Myomesin 1 (MYOM1)

Alternative Name: Myomesin-1

Background: Rabbit Anti-Myomesin-1 Polyclonal Antibody,MYOM1, Myomesin-1, 190 kDa connectin-associated protein, 190 kDa titin-associated protein, Myomesin family member 1,The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.,Myomesin-1

Gene ID: 8736

UniProt: P52179