MYO9B antibody (AA 280-360)

Catalog No. ABIN7222626

This anti-MYO9B antibody is a Rabbit Polyclonal antibody detecting MYO9B in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for MYO9B antibody (AA 280-360) (ABIN7222626)

Target: MYO9B (Myosin IXB (MYO9B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO9B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYO9B Antibody

Binding Specificity: AA 280-360

Purpose: Myosin IXb Polyclonal Antibody

Specificity: Myosin IXb Polyclonal Antibody detects endogenous levels of Myosin IXb protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Myosin IXb at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MYO9B

Target: MYO9B (Myosin IXB (MYO9B))

Alternative Name: Myosin IXb

Background: Rabbit Anti-Myosin IXb Polyclonal Antibody,MYO9B, MYR5, Unconventional myosin-IXb, Unconventional myosin-9b,MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin, it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for MYO9B.,Unconventional myosin-IXb

Molecular Weight: observerd band 250kDa

Gene ID: 4650

UniProt: Q13459