MYO5A antibody (AA 1760-1840)

Catalog No. ABIN7222624

The Rabbit Polyclonal anti-MYO5A antibody is suitable to detect MYO5A in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MYO5A antibody (AA 1760-1840) (ABIN7222624)

Target: MYO5A (Myosin VA (MYO5A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYO5A Antibody

Binding Specificity: AA 1760-1840

Purpose: Myosin VA Polyclonal Antibody

Specificity: Myosin VA Polyclonal Antibody detects endogenous levels of Myosin VA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Myosin VA at AA range: 1760-1840

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MYO5A

Target: MYO5A (Myosin VA (MYO5A))

Alternative Name: Myosin VA

Background: Rabbit Anti-Myosin VA Polyclonal Antibody,MYO5A, MYH12, Unconventional myosin-Va, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myosin-12, Myoxin,MYO5A is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by MYO5A is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.,Unconventional myosin-Va

Molecular Weight: observerd band 220kDa

Gene ID: 4644

UniProt: Q9Y4I1

Pathways: Hormone Transport, Peptide Hormone Metabolism