NPHP1 antibody (AA 510-590)

Catalog No. ABIN7230076

The Rabbit Polyclonal anti-NPHP1 antibody is suitable to detect NPHP1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for NPHP1 antibody (AA 510-590) (ABIN7230076)

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NPHP1 Antibody

Binding Specificity: AA 510-590

Purpose: NPHP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NPHP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human NPHP1 protein at AA range: 510-590

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NPHP1

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Alternative Name: NPHP1

Background: Rabbit Anti-NPHP1 Polyclonal Antibody,Nephrocystin-1, Juvenile nephronophthisis 1 protein,NPHP1 (Nephrocystin 1) is a Protein Coding gene. Diseases associated with NPHP1 include Senior-Loken Syndrome-1 and Nephronophthisis 1, Juvenile. Among its related pathways are Organelle biogenesis and maintenance and Regulation of PLK1 Activity at G2/M Transition. NPHP1 encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures.,NPHP1

Molecular Weight: observerd band 80kDa

Gene ID: 4867

UniProt: O15259