Nerve Growth Factor antibody (Internal Region)

Catalog No. ABIN7216080

The Rabbit Polyclonal anti-Nerve Growth Factor antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect Nerve Growth Factor in samples from Human, Rat and Mouse.

Quick Overview for Nerve Growth Factor antibody (Internal Region) (ABIN7216080)

Target: Nerve Growth Factor (NGF)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nerve Growth Factor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Nerve Growth Factor Antibody

Binding Specificity: Internal Region

Purpose: NGF Polyclonal Antibody

Specificity: NGF Polyclonal Antibody detects endogenous levels of NGF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human NGF

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Nerve Growth Factor

Target: Nerve Growth Factor (NGF)

Alternative Name: NGF

Background: Rabbit Anti-NGF Polyclonal Antibody,NGF, NGFB, Beta-nerve growth factor, Beta-NGF,NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis.,Beta-nerve growth factor

Molecular Weight: observerd band 27kDa

Gene ID: 4803

UniProt: P01138

Pathways: Regulation of Cell Size