UNC5B antibody (AA 350-430)

Catalog No. ABIN7232040

The Rabbit Polyclonal anti-UNC5B antibody has been validated for WB and ELISA. It is suitable to detect UNC5B in samples from Human, Mouse and Rat.

Quick Overview for UNC5B antibody (AA 350-430) (ABIN7232040)

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UNC5B Antibody

Binding Specificity: AA 350-430

Purpose: UNC5B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UNC5B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UNC5B protein at AA range: 350-430

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Alternative Name: UNC5B

Background: Rabbit Anti-UNC5B Polyclonal Antibody,Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B, p53-regulated receptor for death and life protein 1, p53RDL1,UNC5B (Unc-5 Netrin Receptor B) is a Protein Coding gene. Among its related pathways are Netrin-1 signaling and Netrin Signaling. UNC5B encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for UNC5B.,UNC5B

Molecular Weight: observerd band 103kDa

Gene ID: 219699

UniProt: Q8IZJ1