NEURL antibody (AA 190-270)

Catalog No. ABIN7225840

The Rabbit Polyclonal anti-NEURL antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect NEURL in samples from Human.

Quick Overview for NEURL antibody (AA 190-270) (ABIN7225840)

Target: NEURL (Neuralized Homolog (Drosophila) (NEURL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEURL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NEURL Antibody

Binding Specificity: AA 190-270

Purpose: Neuralized-1 Polyclonal Antibody

Specificity: Neuralized-1 Polyclonal Antibody detects endogenous levels of Neuralized-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Neuralized-1 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NEURL

Target: NEURL (Neuralized Homolog (Drosophila) (NEURL))

Alternative Name: Neuralized-1

Background: Rabbit Anti-Neuralized-1 Polyclonal Antibody,NEURL, NEURL1, NEURL1A, RNF67, Neuralized-like protein 1A, h-neu, h-neuralized 1, RING finger protein 67,NEURL1B (neuralized homolog 1B), also known as neur2 or NEURL3, is a 555 amino acid protein that functions as an E3 ubiquitin-protein ligase. Involved in protein ubiquitination, NEURL1B contains two NHR (neuralized homology repeat) domains and one RING-type zinc finger. NEURL4 (neuralized homolog 4 (Drosophila)), also known as neuralized-like protein 4, is a 1,562 amino acid protein that is highly expressed in a wide variety of tissues. Containing six NHR (neuralized homology repeat) domains, NEURL4 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 17p13.1.,Neuralized-like protein 1A

Molecular Weight: observerd band 62kDa

Gene ID: 9148

UniProt: O76050

Pathways: Notch Signaling, EGFR Signaling Pathway