NCALD antibody (AA 370-450)
Quick Overview for NCALD antibody (AA 370-450) (ABIN7225346)
Target
See all NCALD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 370-450
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Purpose
- Neurocalcin δ Polyclonal Antibody
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Specificity
- Neurocalcin δ Polyclonal Antibody detects endogenous levels of Neurocalcin δ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Neurocalcin delta at AA range: 370-450
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NCALD (Neurocalcin delta (NCALD))
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Alternative Name
- Neurocalcin delta
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Background
- Rabbit Anti-Neurocalcin δ Polyclonal Antibody,NCALD, Neurocalcin-delta,NCALD (neurocalcin delta) encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels, however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of NCALD have been determined, all of which encode the same protein, additional variants may exist but their biological validity has not been determined.,Neurocalcin-delta
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Gene ID
- 83988
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UniProt
- P61601
Target
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