NMBR antibody (AA 190-270)

Catalog No. ABIN7222774

This anti-NMBR antibody is a Rabbit Polyclonal antibody detecting NMBR in WB, ELISA and IF. Suitable for Human, Mouse and Rat.

Quick Overview for NMBR antibody (AA 190-270) (ABIN7222774)

Target: NMBR (Neuromedin B Receptor (NMBR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMBR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NMBR Antibody

Binding Specificity: AA 190-270

Purpose: NMBR Polyclonal Antibody

Specificity: NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human NMBR at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NMBR

Target: NMBR (Neuromedin B Receptor (NMBR))

Alternative Name: NMBR

Background: Rabbit Anti-NMBR Polyclonal Antibody,NMBR, Neuromedin-B receptor, NMB-R, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor,NMBR encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.,Neuromedin-B receptor

Molecular Weight: observerd band 43kDa

Gene ID: 4829

UniProt: P28336