NMBR antibody (AA 221-270)

Catalog No. ABIN1535786

The Rabbit Polyclonal anti-NMBR antibody (ABIN1535786) specifically detects NMBR in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NMBR antibody (AA 221-270) (ABIN1535786)

Target: NMBR (Neuromedin B Receptor (NMBR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMBR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NMBR Antibody

Binding Specificity: AA 221-270

Purpose: NMBR Antibody

Specificity: NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NMBR

Target: NMBR (Neuromedin B Receptor (NMBR))

Alternative Name: NMBR

Background:

Synonyms: NMBR, Neuromedin-B receptor, NMB-R, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor

Background: This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

Gene Name: NMBR

Protein Name: Neuromedin-B receptor

Molecular Weight: 43 kDa

Gene ID: 4829

OMIM: 162341

UniProt: P28336