NKX2-8 antibody (AA 10-90)

Catalog No. ABIN7220988

This Rabbit Polyclonal antibody specifically detects NKX2-8 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for NKX2-8 antibody (AA 10-90) (ABIN7220988)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX2-8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKX2-8 Antibody

Binding Specificity: AA 10-90

Purpose: Nkx-2.8 Polyclonal Antibody

Specificity: Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Nkx-2.8 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Alternative Name: Nkx-2.8

Background: Rabbit Anti-Nkx-2.8 Polyclonal Antibody,The NK2 homeobox 8 encoded by NKX2-8 is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.,Homeobox protein Nkx-2.8

Molecular Weight: observerd band 26kDa

Gene ID: 26257

UniProt: Q8IUT7