NCOA4 antibody (AA 320-400)

Catalog No. ABIN7213654

This anti-NCOA4 antibody is a Rabbit Polyclonal antibody detecting NCOA4 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for NCOA4 antibody (AA 320-400) (ABIN7213654)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NCOA4 Antibody

Binding Specificity: AA 320-400

Purpose: ARA70 Polyclonal Antibody

Specificity: ARA70 Polyclonal Antibody detects endogenous levels of ARA70 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ARA70 at AA range: 320-400

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: ARA70

Background: Rabbit Anti-ARA70 Polyclonal Antibody,NCOA4, ARA70, ELE1, RFG, Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein,NCOA4 encodes an androgen receptor coactivator. The encoded protein (nuclear receptor coactivator 4) interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.,Nuclear receptor coactivator 4

Gene ID: 8031

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway