OPCML antibody (Internal Region)

Catalog No. ABIN7216154

This Rabbit Polyclonal antibody specifically detects OPCML in WB and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Monkey.

Quick Overview for OPCML antibody (Internal Region) (ABIN7216154)

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPCML antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OPCML Antibody

Binding Specificity: Internal Region

Purpose: OBCAM Polyclonal Antibody

Specificity: OBCAM Polyclonal Antibody detects endogenous levels of OBCAM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human OBCAM

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for OPCML

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Alternative Name: OBCAM

Background: Rabbit Anti-OBCAM Polyclonal Antibody,OPCML, IGLON1, OBCAM, Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1,OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein. Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Opioid-binding protein

Molecular Weight: observerd band 58kDa

Gene ID: 4978

UniProt: Q14982