ORC6 antibody (AA 160-240)

Catalog No. ABIN7230410

The Rabbit Polyclonal anti-ORC6 antibody has been validated for WB and ELISA. It is suitable to detect ORC6 in samples from Human and Mouse.

Quick Overview for ORC6 antibody (AA 160-240) (ABIN7230410)

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ORC6 Antibody

Binding Specificity: AA 160-240

Purpose: ORC6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ORC6 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ORC6 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Alternative Name: ORC6

Background: Rabbit Anti-ORC6 Polyclonal Antibody,Origin recognition complex subunit 6,The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by ORC6 is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.,ORC6

Molecular Weight: observerd band 27kDa

Gene ID: 23594

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA