PAKbeta (pSer154) antibody

Catalog No. ABIN7222928

This anti-not_set antibody is a Rabbit Polyclonal antibody detecting not_set in ELISA, WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PAKbeta (pSer154) antibody (ABIN7222928)

Target: PAKbeta

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: pSer154

Purpose: PAKβ (phospho Ser154) Polyclonal Antibody

Specificity: Phospho-PAKβ (S154) Polyclonal Antibody detects endogenous levels of PAKβ protein only when phosphorylated at S154.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human PAKbeta Phospho-Ser154

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: PAKbeta

Background: Rabbit Anti-PAKβ (phospho Ser154) Polyclonal Antibody,PAK3, OPHN3, Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3,The protein encoded by PAK3 is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like P21, CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in PAK3 are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.,serine threonine-protein kinase PAK 3

Molecular Weight: observerd band 72kDa

Gene ID: 5063

UniProt: O75914