HRPT2 antibody (AA 51-100)

Catalog No. ABIN7230498

The Rabbit Polyclonal anti-HRPT2 antibody has been validated for WB and ELISA. It is suitable to detect HRPT2 in samples from Human, Mouse and Rat.

Quick Overview for HRPT2 antibody (AA 51-100) (ABIN7230498)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRPT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HRPT2 Antibody

Binding Specificity: AA 51-100

Purpose: Parafibromin Polyclonal Antibody

Specificity: This antibody detects endogenous levels of Parafibromin

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Parafibromin protein at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: Parafibromin

Background: Rabbit Anti-Parafibromin Polyclonal Antibody,Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein,CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.,Parafibromin

Molecular Weight: observerd band 60kDa

Gene ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance