PER1 antibody (AA 1110-1190)

Catalog No. ABIN7230586

The Rabbit Polyclonal anti-PER1 antibody has been validated for WB and ELISA. It is suitable to detect PER1 in samples from Human, Mouse and Rat.

Quick Overview for PER1 antibody (AA 1110-1190) (ABIN7230586)

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PER1 Antibody

Binding Specificity: AA 1110-1190

Purpose: PER1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PER1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PER1 protein at AA range: 1110-1190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Alternative Name: PER1

Background: Rabbit Anti-PER1 Polyclonal Antibody,Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui,PER1 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER1 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER1 may increase the risk of getting certain cancers. Alternative splicing has been observed in PER1, however, these variants have not been fully described.,PER1

Molecular Weight: observerd band 141kDa

Gene ID: 5187

UniProt: O15534

Pathways: Photoperiodism