PEX6 antibody (AA 480-560)

Catalog No. ABIN7230598

The Rabbit Polyclonal anti-PEX6 antibody is suitable to detect PEX6 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for PEX6 antibody (AA 480-560) (ABIN7230598)

Target: PEX6 (Peroxisomal Biogenesis Factor 6 (PEX6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PEX6 Antibody

Binding Specificity: AA 480-560

Purpose: Rabbit Anti-PEX6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PEX6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PEX6 protein at AA range: 480-560

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEX6

Target: PEX6 (Peroxisomal Biogenesis Factor 6 (PEX6))

Alternative Name: PEX6

Background: Peroxisome assembly factor 2, PAF-2, Peroxin-6, Peroxisomal biogenesis factor 6, Peroxisomal-type ATPase 1PEX6 (Peroxisomal Biogenesis Factor 6) is a Protein Coding gene. Diseases associated with PEX6 include Peroxisome Biogenesis Disorder 4A and Heimler Syndrome 2. Among its related pathways are Peroxisome. PEX6 encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in PEX6 cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. Several transcript variants encoding different isoforms have been found for PEX6.

Molecular Weight: 107kD

Gene ID: 5190

UniProt: Q13608